Now offering custom senolytic compound development and clinical study services - Introduction
The hardest part of cutting is losing muscle with the fat, not losing weight. With over 650 million adults obese worldwide, consumers want muscle-preserving fat loss. Botagovy® Metabolic Solutions: natural compounds that activate GLP-1 receptors for body composition and muscle preservation.
The Science Behind Natural GLP-1 Activation
GLP-1 (Glucagon-like peptide-1) receptors play a crucial role in glucose homeostasis, appetite regulation, and weight management. We have identified over 35 berberine derivatives and analogues that naturally activate these pathways while targeting complementary mechanisms including AMPK, SGLT, DPP-4, and HMG-CoA reductase.
Lead Compounds and Their Mechanisms
Capsiate: The Metabolic Accelerator
Derived from sweet peppers, capsiate offers the thermogenic benefits of capsaicin without the burning sensation. Our studies demonstrate its ability to enhance fat oxidation while supporting healthy blood sugar levels.
Corylin: The Dual-Action Compound
This flavonoid compound targets both glucose metabolism and inflammatory pathways, an ideal candidate for comprehensive body-composition support.
Curcumins: Beyond Anti-Inflammation
While known for anti-inflammatory properties, our optimized curcumin formulations show remarkable GLP-1 receptor activation and insulin sensitivity enhancement, directing nutrients toward muscle.
Clinical Applications and Market Potential
The global GLP-1 receptor agonist market is projected to reach $17.3 billion by 2027. Botagovy® positions itself at the intersection of natural health and pharmaceutical efficacy, offering safer, more accessible alternatives to synthetic drugs.
Future Directions
Our ongoing research focuses on synergistic combinations and enhanced bioavailability for next-generation body composition solutions.
From Cellular Science to Performance
Botagovy® is the entry point to Botanicure’s three core pillars: Muscle & Strength, Brain & Cognition, and Sports Performance. By combining GLP-1 activation, AMPK signaling, and insulin-sensitivity enhancement, our natural compound library helps brands deliver real, visible body-composition results without muscle loss. Partner with Botanicure to bring next-generation muscle-preserving solutions to market: the foundation of our Muscle & Strength innovation pipeline.
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