Piperlongumine (Synonyms: Piplartine)

Piperlongumine  (Synonyms:  Piplartine)

Piperlongumine (PPLGM, Piplartine), a natural alkaloid from Piper longum L., increases the level of reactive oxygen species (ROS) and selectively kills cancer cells. It is a direct TrxR1 inhibitor with suppressive activity against gastric cancer and a novel inhibitor of CRM1; also an inhibitor of PI3K/Akt/mTOR in human breast cancer cells.

Piperlongumine Chemical Structure

Piperlongumine Chemical Structure

CAS No. : 20069-09-4